2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

PDF 2.67 MB

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-159915
    Se2h
    		Inhibitor
    Se2h is a cruzain inhibitor that exhibits strong activity against the intracellular amastigotes of Trypanosoma cruzi (EC50 < 1 μM, SI > 10), with an inhibitory activity against cruzain of IC50 < 100 nM (SI > 5.55). Compared to Benznidazole (HY-B1548) and the cruzain inhibitor K777 (HY-119293), Se2h shows superior selectivity and inhibition, while its selenazole structure reduces selenium-related toxicity. Se2h exhibits antiparasitic activity and holds promise for research in Chagas disease.
    Se2h
  • HY-B1194R
    Tetramisole hydrochloride (Standard)
    		Inhibitor
    Tetramisole hydrochloride (Standard) is the analytical standard of Tetramisole (hydrochloride). This product is intended for research and analytical applications. Tetramisole hydrochloride is an orally active, selective inward rectifier potassium channel agonist with an EC50 of approximately 30 μM for the Kir2.1 subunit. Tetramisole hydrochloride is also an anti-nematode agent that blocks neuromuscular transmission by non-competitive depolarization. Tetramisole hydrochloride promotes the forward transport of Kir2.1 channels, hyperpolarizes the resting potential (RP), shortens the action potential duration (APD), inhibits intracellular calcium overload and the PKA signaling pathway, and exerts anti-arrhythmic and anti-myocardial remodeling activities. Tetramisole hydrochloride can be used in cardiac electrophysiology research and research related to myocardial ischemia and heart failure.
    Tetramisole hydrochloride (Standard)
  • HY-14895AR
    Fabomotizole hydrochloride (Standard)
    		Inhibitor
    Fabomotizole (hydrochloride) (Standard) is the analytical standard of Fabomotizole (hydrochloride). This product is intended for research and analytical applications. Fabomotizole (CM346) hydrochloride is a compound with anxiolytic and neuroprotective activities. Fabomotizole (CM346) hydrochloride also has activity against Giardia lamblia and has the potential to inhibit giardiasis.
    Fabomotizole hydrochloride (Standard)
  • HY-116552
    KAR425
    		Inhibitor
    KAR425 is a potent and orally active antimalarial agent. KAR425 shows antimalarial activity against the Chloroquine-sensitive (CQS) D6, the Chloroquine-resistant (CQR) Dd2, and 7G8 strains of Plasmodium falciparum, with IC50 values of 62 nM, 55 nM, and 60 nM, respectively.
    KAR425
  • HY-163804
    Cyprocide-B
    		Inhibitor
    Cyprocide-B is activated by Cytochrome P450 and converted to electrophilic metabolites that selectively kill nematodes C. elegans. Cyprocide-B is promising for research of selective nematicide.
    Cyprocide-B
  • HY-173461
    Anti-Trypanosoma cruzi agent-7
    		Inhibitor
    Anti-Trypanosoma cruzi agent-7 (compound 1) is a potent Trypanosoma cruzi inhibitor with an EC50 of 1.26 µM. Anti-Trypanosoma cruzi agent-7 can be used in the study of Chagas disease.
    Anti-Trypanosoma cruzi agent-7
  • HY-128214
    IMPDH-IN-3
    		Inhibitor
    IMPDH-IN-3 (Compound C67) is an inhibitor of C. parvum IMPDH (CpIMPDH) with an IC50 of 35 nM. IMPDH-IN-3 can be used in the research of anti-Cryptosporidium drugs.
    IMPDH-IN-3
  • HY-N15096
    Milbemycin α14
    		Inhibitor
    Milbemycin α14 is an antibiotic and has the effect of killing nematodes and mites.
    Milbemycin α14
  • HY-N1451R
    Betulonic acid (Standard)
    		Inhibitor
    Betulonic acid (Standard) is the analytical standard of Betulonic acid. This product is intended for research and analytical applications. Betulonic acid (Betunolic acid), a naturally occurring triterpene, is found in many plants. Betulonic acid has anti-tumor, anti-inflammatory, antiparasitic and anti-viral (HSV-1) activities.
    Betulonic acid (Standard)
  • HY-12724AR
    Guanabenz hydrochloride (Standard)
    		Inhibitor
    Guanabenz (hydrochloride) (Standard) is the analytical standard of Guanabenz (hydrochloride). This product is intended for research and analytical applications. Guanabenz hydrochloride is an orally active α-2-adrenoceptor agonist. Guanabenz hydrochloride has antihypertensive effect and antiparasitic activity. Guanabenz hydrochloride interferes ER stress-signalling and has protective effects in cardiac myocytes. Guanabenz hydrochloride also is used for the research of high blood pressure.
    Guanabenz hydrochloride (Standard)
  • HY-19285R
    Sulfaclozine (Standard)
    		Inhibitor
    Sulfaclozine (Standard) is the analytical standard of Sulfaclozine. This product is intended for research and analytical applications. Sulfaclozine (Sulfachloropyrazine) is an efficacious sulphonamide derivative with antibacterial and anticoccidial effects. Sulfaclozine is commonly used for the treatment of various poultry diseases (particularly, collibacteriosis, fowl cholera and coccidiosis).
    Sulfaclozine (Standard)
  • HY-W654139
    5'-Deoxy-5'-(methylthio)adenosine-d3
    5'-Deoxy-5'-(methylthio)adenosine-d3 is deuterium labeled 5'-Methylthioadenosine. 5'-Methylthioadenosine (5'-(Methylthio)-5'-deoxyadenosine) is a nucleoside generated from S-adenosylmethionine (SAM) during polyamine synthesis. 5'-Methylthioadenosine suppresses tumors by inhibiting tumor cell proliferation, invasion, and the induction of apoptosis while controlling the inflammatory micro-environments of tumor tissue. 5'-Methylthioadenosine and its associated materials have striking regulatory effects on tumorigenesis.
    5'-Deoxy-5'-(methylthio)adenosine-d<sub>3</sub>
  • HY-12785R
    Albendazole sulfoxide (Standard)
    		Inhibitor
    Albendazole sulfoxide (Standard) is the analytical standard of Albendazole sulfoxide. This product is intended for research and analytical applications. Albendazole sulfoxide (Ricobendazole), the main active metabolite of Albendazole, exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes.
    Albendazole sulfoxide (Standard)
  • HY-W049875R
    Nitroxynil (Standard)
    		Inhibitor
    Nitroxynil (Standard) is the analytical standard of Nitroxynil. This product is intended for research and analytical applications. Nitroxynil, anthelmintic agent, is active against parasites in both adult and immature stages. Nitroxynil is widely used for the research of infection of Fasciola hepatica.
    Nitroxynil (Standard)
  • HY-N14536
    Dihydrohypothemycin
    		Inhibitor
    Dihydrohypothemycin has anti-tsutsugamushi activity.
    Dihydrohypothemycin
  • HY-170963
    LASSBio-1985
    		Inhibitor
    LASSBio-1985 is an NHLd inhibitor (nucleoside hydrolase from Leishmania donovani), with a Ki of 79 μM and an IC50 of 84.6 μM. LASSBio-1985 exhibits selective toxicity against Leishmania parasites, with no toxicity to mammalian cells, making it a promising candidate for research in the field of anti-infective therapies.
    LASSBio-1985
  • HY-19567R
    PK 11195 (Standard)
    		Inhibitor
    PK 11195 (Standard) is the analytical standard of PK 11195. This product is intended for research and analytical applications. PK 11195 (RP 52028) is a ligand of translocator protein (TSPO), which targets Leishmania chemotherapy, with IC50s of 14.2 μM, 8.2 μM, 3.5 μM for L. amazonensis, L. major and L. braziliensis, respectively.
    PK 11195 (Standard)
  • HY-N8181
    1,3-Linolein-2-Olein
    		Inhibitor
    1,3-Linolein-2-Olein, a triglyceride, is an antileishmanial agent. 1,3-Linolein-2-Olein inhibits promatigotes of the parasite (IC50=0.079 ug/ml) and inhibits the growth of amastigotes (IC50= 40.03 ug/ml).
    1,3-Linolein-2-Olein
  • HY-50730R
    Asparagusic acid (Standard)
    		Inhibitor
    Asparagusic acid (Standard) is the analytical standard of Asparagusic acid. This product is intended for research and analytical applications. Asparagusic acid is a sulfur-containing flavor component produced by Asparagus officinalis Linn., with anti-parasitic effect. Asparagusic acid is a plant growth inhibitor.
    Asparagusic acid (Standard)
  • HY-119900R
    Carnidazole (Standard)
    		Inhibitor
    Carnidazole (Standard) is the analytical standard of Carnidazole. This product is intended for research and analytical applications. Carnidazole is an antiprotozoal agent of the nitroimidazole class. Carnidazole is used for the research of Trichomonas infection.
    Carnidazole (Standard)
Parasite Isoform Comparison

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.