2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-170780
    DSM1465
    		Inhibitor
    DSM1465 (Compound 82) is a potent, selective inhibitor of P. falciparum dihydroorotate dehydrogenase (PfDHODH) with an IC50 value of 15 nM, inhibits P. falciparum 3D7 (Pf3D7) parasites with an EC50 value of 1.4 nM. DSM1465 shows potent in vivo activity in the humanized P. falciparum mouse model.
    DSM1465
  • HY-111817A
    (Rac)-ACT-451840
    		Inhibitor
    (Rac)-ACT-451840 is an isomer of ACT-451840 that exhibits significant antimalarial effects. (Rac)-ACT-451840 exhibits significant antimalarial activity against P. berghei-infected mice at a dose of 20 mg/kg (ED90=13 mg/kg), and has an inhibitory effect at a dose of 300 mg/kg. The ED90 of (Rac)-ACT-451840 in the P. falciparum humanized immunodeficient mouse model is 3.7 mg/kg. (Rac)-ACT-451840 is similar to artemisinin, with a rapid onset of action but requires repeated high doses.
    (Rac)-ACT-451840
  • HY-N0402R
    Artemether (Standard)
    		Inhibitor
    Artemether (Standard) is the analytical standard of Artemether. This product is intended for research and analytical applications. Artemether is an anti-malarial compound that targets drug-resistant strains of falciparum malaria.
    Artemether (Standard)
  • HY-W587957
    Gypsogenic acid
    		Inhibitor
    Gypsogenic acid is a triterpenoid acid that can be isolated from Miconia stenostachya and has antibacterial and trypanoidal activities. The MICs values of Gypsogenic acid for the oral bacterial pathogens Enterococcus faecalis, Streptococcus salivarius, Streptococcus haematococcus, Streptococcus mutans and sobrinus were 50-200 μg/mL. Gypsogenic acid can induce blood cortensite cleavage in isolated mice with IC50 56.6 μM.
    Gypsogenic acid
  • HY-118288
    Aurachin B
    Aurachin B is an alkaloid with a 3-hydroxyquinoline N-oxide core.
    Aurachin B
  • HY-12651AR
    Primaquine (Standard)
    		Inhibitor
    Primaquine (Standard) is the analytical standard of Primaquine. This product is intended for research and analytical applications. Primaquine is a potent antimalaria agent and a potent gametocytocide in falciparum malaria. Primaquine prevents relapse in vivax and ovale malaria.
    Primaquine (Standard)
  • HY-B0688R
    Dapsone (Standard)
    		Inhibitor 99.77%
    Dapsone (Standard) is the analytical standard of Dapsone. This product is intended for research and analytical applications. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al.
    Dapsone (Standard)
  • HY-118494R
    Ascaridole (Standard)
    		Inhibitor
    Ascaridole (Standard) is the analytical standard of Ascaridole. This product is intended for research and analytical applications. Ascaridole is an anthelmintic and also has antimalarial activity.
    Ascaridole (Standard)
  • HY-16762R
    Artefenomel (Standard)
    		Inhibitor
    Artefenomel (Standard) is the analytical standard of Artefenomel. This product is intended for research and analytical applications. Artefenomel (OZ439) is an orally active, synthetic anti-malarial compound containing an artemisinin pharmacophore with a mechanism of action similar to that of artemisinin. Artefenomel has antiviral activity against SARS-CoV-2.
    Artefenomel (Standard)
  • HY-13832S
    Atovaquone-d4
    		Inhibitor 99.8%
    Atovaquone-d4 is the deuterium labeled Atovaquone. Atovaquone is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia[1].
    Atovaquone-d<sub>4</sub>
  • HY-101476R
    Emodepside (Standard)
    		Inhibitor
    Emodepside (Standard) is the analytical standard of Emodepside. This product is intended for research and analytical applications. Emodepside (PF 1022-221) is a cyclooctadepsipeptide with broad-spectrum anthelmintic activity.
    Emodepside (Standard)
  • HY-12642AR
    Diethylcarbamazine (Standard)
    		Inhibitor
    Diethylcarbamazine (Standard) is the analytical standard of Diethylcarbamazine. This product is intended for research and analytical applications. Diethylcarbamazine is a microfilaricidal agent used originally in onchocerciasis and lymphatic filiariasis study.
    Diethylcarbamazine (Standard)
  • HY-B2138R
    Ethopabate (Standard)
    		Inhibitor
    Ethopabate (Standard) is the analytical standard of Ethopabate (HY-B2138). This product is intended for research and analytical applications. Ethopabate (Ethyl pabate) is an orally active antiparasitic agent. Ethopabate is often used in combination with Amprolium hydrochloride (HY-B0937A) and others to prevent and treat poultry coccidiosis, leucosis, and other diseases.
    Ethopabate (Standard)
  • HY-151150
    Trypanothione synthetase-IN-2
    Trypanothione synthetase-IN-2 (Compound 3) is a competitive Leishmania infantum trypanothione synthetase (TryS) inhibitor with an IC50 of 5.4 μM when triamine spermidine is as polyamine S.
    Trypanothione synthetase-IN-2
  • HY-136081
    Hexamidine
    		Inhibitor
    Hexamidine has amoebicidal effect that can be used for the research of Acanthamoeba keratitis.
    Hexamidine
  • HY-12404R
    Diminazene aceturate (Standard)
    		Inhibitor
    Diminazene (aceturate) (Standard) is the analytical standard of Diminazene (aceturate). This product is intended for research and analytical applications. Diminazene aceturate (Diminazene diaceturate) is an anti-trypanosome agent for livestock. The main biochemical mechanism of the trypanocidal actions of Diminazene aceturate is by binding to trypanosomal kinetoplast DNA (kDNA) in a non-intercalative manner through specific interaction with sites rich in adenine-thymine base pairs. Diminazene aceturate is also an angiotensin-converting enzyme 2 (ACE2) activator and has strong and potent anti-inflammatory properties.
    Diminazene aceturate (Standard)
  • HY-117146
    Indoxacarb
    Indoxacarb ((S)-DPX-JW062) is an oxathiazole insecticide with activity against a wide range of insect pests. Indoxacarb is used in forest pest management to control insect pests, and its toxicity has significant effects on adult individuals of the predatory stink bug Podisus distinctus. Indoxacarb showed high toxicity to P. distinctus at a lethal concentration (LC50 = 2.62 g L-1). Indoxacarb treatment significantly reduced the survival rate of P. distinctus, with the survival rate of individuals exposed to 2.62 g L-1 decreasing to 40.7%. Indoxacarb also reduced the respiration rate of P. distinctus from 18.45 to 14.41 μL CO2 h-1, and inhibited its food intake. P. distinctus showed hyperexcitatory responses after Indoxacarb treatment.
    Indoxacarb
  • HY-168959
    Antiparasitic agent-25
    		Inhibitor
    Antiparasitic agent-25 (Compounds 11) is an orally active antiparasitic agent. Antiparasitic agent-25 inhibits both parasite invasion and replication ability and has irreversible action against Toxoplasma gondii, significantly reducing the replication rate of Toxoplasma gondii with an IC50 value of 6.33 μM, and demonstrates low cytotoxicity with a CC50 value of 285 μM.
    Antiparasitic agent-25
  • HY-115584B
    Lufenuron, (-)-
    		Inhibitor
    Lufenuron, (-)- is an active isomer form of Lufenuron. Lufenuron is a lipophilic benzoyl urea insecticide and chitin synthesis inhibitor that can be used for flea and fish lice control. Lufenuron inhibits the molting of arthropods.
    Lufenuron, (-)-
  • HY-12361R
    PF 1022A (Standard)
    		Inhibitor
    PF 1022A (Standard) is the analytical standard of PF 1022A. This product is intended for research and analytical applications. PF 1022A is a cyclooctadepsipeptide with broadspectrum anthelmintic properties produced by fermentation of the fungus Mycelia sterilia. PF 1022A is a channel-forming ionophore. PF 1022A showes strong anthelmintic activities against Ascaridia galli in chickens. PF 1022A also can be used for angiostrongyliasis research[1][2][3].
    PF 1022A (Standard)
Parasite Isoform Comparison

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